CJC-1295 / Ipamorelin
Growth Hormone SecretagogueAlso known as: CJC-1295 DAC, CJC/Ipa, Modified GRF 1-29
A combination of a growth hormone releasing hormone analog (CJC-1295) and a selective growth hormone secretagogue (Ipamorelin), used to stimulate endogenous GH production.
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Aggregated data reflects community experience (38 total self-reports), not scientific consensus. This is not a clinical trial.
Outcome Breakdown
Based on 38 community reports
Reported Side Effects
Frequency among reporters who noted side effects
Common Forms
What the Scientific Literature Says
CJC-1295 has Phase II data showing sustained GH elevation. Ipamorelin is a selective ghrelin receptor agonist with Phase II safety data. The combination is not FDA-approved. Theoretically mimics physiological GH pulsatility. Long-term safety data is lacking.
External Discussions & Signal
BetaWhat the rest of the internet is saying about CJC-1295 / Ipamorelin. Moderation-filtered, linked to the source — we don’t re-host content.
CJC/Ipa 6-month log: DEXA, IGF-1, Oura — what changed and what didn't
100/100mcg nightly, 5-on-2-off. IGF-1: 134 → 251. DEXA at 3 and 6 months: −4.1lb fat / +2.3lb lean. Oura deep sleep +22 min avg. Zero effect on vertical jump or 5k time.
Well-documented: DEXA + IGF-1 + wearable data across 6 months.
Carpal tunnel on CJC/Ipa — dose too high?
Been on 200/200 nightly for 3 weeks, starting to get pins and needles in both hands on waking. Is this the classic GH-induced water retention or something else?
Consistent with evidence: Carpal tunnel sx from GH-secretagogue-induced fluid retention is well-characterized.
Pulled via the Reddit API from subreddits matched to CJC-1295 / Ipamorelin. Threads are ranked by a fact-check pass: well-documented → consistent with evidence → anecdotal. Unsupported-claim and sourcing posts are hidden by default. Click through to read on Reddit — we don’t re-host content.
Community Reports (2 displayed of 38)
Add yours12-week nightly CJC/Ipa protocol showed significant improvements in sleep architecture (Oura-tracked), body composition (DEXA-confirmed), and IGF-1 levels. Comprehensive biomarker tracking supports high confidence.
16-week CJC/Ipa protocol alongside TRT showed improved sleep, favorable body recomposition (DEXA-confirmed), and significant IGF-1 increase. Early side effects (water retention, tingling) resolved. Concurrent TRT complicates attribution.