Semaglutide
GLP-1 AgonistAlso known as: Ozempic, Wegovy, Rybelsus
A glucagon-like peptide-1 receptor agonist FDA-approved for type 2 diabetes and obesity. Widely used off-label for weight management.
Filter by Goal
Aggregated data reflects community experience (63 total self-reports), not scientific consensus. This is not a clinical trial.
Outcome Breakdown
Based on 63 community reports
Reported Side Effects
Frequency among reporters who noted side effects
Common Forms
What the Scientific Literature Says
Extensive clinical trial data (STEP, SUSTAIN, PIONEER programs). FDA-approved at 2.4mg weekly for chronic weight management with ~15% body weight reduction. Well-characterized side effect profile dominated by GI effects. Cardiovascular benefit demonstrated in SELECT trial.
External Discussions & Signal
BetaWhat the rest of the internet is saying about Semaglutide. Moderation-filtered, linked to the source — we don’t re-host content.
1 year on sema — 58lbs down, A1c 7.4 → 5.4, full labs + CGM data
Complete year-long log. Started 0.25mg, titrated to 1.7mg maintenance. Lost 58lbs (24% body weight), A1c normalized, time-in-range 62% → 94%. Triglycerides 280 → 118. Full spreadsheet + CGM screenshots in the post.
Well-documented: Comprehensive biomarker tracking, A1c + CGM + lipid panel.
Hair loss on semaglutide — how bad was yours and did it stop?
4 months in, lost maybe 15lbs, but my hair is visibly thinning. Already on biotin and protein is dialed in. Has anyone had this resolve, or did you have to stop?
Consistent with evidence: Telogen effluvium from rapid weight loss is well-documented.
Hidden by moderation
Unregulated sourcing + potentially contaminated product. Safety concern.
Pulled via the Reddit API from subreddits matched to Semaglutide. Threads are ranked by a fact-check pass: well-documented → consistent with evidence → anecdotal. Unsupported-claim and sourcing posts are hidden by default. Click through to read on Reddit — we don’t re-host content.
Community Reports (3 displayed of 63)
Add yours16-week semaglutide titration from 0.5mg to 2.4mg resulted in 12.7% body weight loss with significant metabolic improvements. GI side effects were the main downside but manageable. High confidence due to clear dose-response and biomarker tracking.
8-week semaglutide resulted in weight loss but discontinued due to persistent nausea, hair thinning, fatigue, and negative impact on relationship with food. Effective for weight loss but quality of life tradeoff was not acceptable.
12-week compounded semaglutide titration in T2D patient with comprehensive biomarker tracking. Dramatic glycemic improvement (CGM + A1c), significant weight loss, and lipid improvement. GI side effects manageable. Highest data quality report — CGM provides continuous objective data.