TB-500
Recovery PeptideAlso known as: Thymosin Beta-4, Tβ4
A synthetic version of thymosin beta-4, a naturally occurring peptide involved in tissue repair and regeneration.
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Aggregated data reflects community experience (31 total self-reports), not scientific consensus. This is not a clinical trial.
Outcome Breakdown
Based on 31 community reports
Reported Side Effects
Frequency among reporters who noted side effects
Common Forms
What the Scientific Literature Says
Thymosin beta-4 has been studied in wound healing and corneal repair clinical trials. TB-500 is a synthetic fragment. Limited human data for musculoskeletal applications. Animal studies suggest anti-inflammatory and pro-regenerative effects.
External Discussions & Signal
BetaWhat the rest of the internet is saying about TB-500. Moderation-filtered, linked to the source — we don’t re-host content.
TB-500 for frozen shoulder — 6 weeks in, range of motion up 40°
39F, frozen shoulder for 8 months, PT wasn't moving the needle. Started TB-500 2.5mg twice weekly. By week 3 noticed morning stiffness decrease. Goniometer measurement at week 6: external rotation went from 22° to 62°.
Well-documented: Objective measurement (goniometer), clear baseline.
Anyone else get crazy lethargy on TB-500 loading phase?
Week 2 of loading (5mg 2x/week) and I'm sleeping 10+ hours a night. Is this normal? Posting a poll in the comments to see how common this is.
Pulled via the Reddit API from subreddits matched to TB-500. Threads are ranked by a fact-check pass: well-documented → consistent with evidence → anecdotal. Unsupported-claim and sourcing posts are hidden by default. Click through to read on Reddit — we don’t re-host content.
Community Reports (2 displayed of 31)
Add yours8-week TB-500 + BPC-157 stack for hamstring recovery showed faster return to training than previous injuries. CRP reduction is interesting signal. Stacking makes it hard to attribute effects to either compound alone.
10-week TB-500 + BPC-157 stack for partial meniscus tear avoided surgery in the short term. Significant symptom improvement despite no MRI structural change. Multiple concurrent interventions limit attribution.